Hikal Ltd. High Potency Active Pharmaceutical Ingredient (HPAPI) Laboratory at the Integrated Innovation Centre, Pune is a cGMP-compliant Laboratory equipped with state-of-the-art isolators designed to meet Occupational Exposure Band 5 (OEB-5) requirements. The lab is purpose-built to support the development of complex oncology and specialty molecules, including components of Antibody Drug Conjugates (ADCs), Peptide Drug Conjugates (PDCs), and Proteolysis Targeting Chimeras (PROTACs).
Occupational Exposure Band (OEB-5) compliance with state-of-the-art isolators
Designed for HPAPIs, components of Antibody Drug Conjugates (ADCs), Peptide Drug Conjugates (PDCs), and PROTACs
Supports the entire value chain on lab scale.
Scale flexibility milligrams to ~200 grams per batch
Dedicated clean room facility
ensuring safety
Complements validation,
process safety, solid state,
and flow chemistry.
HPLC & GC systems and
analysis within the HPAPI
Lab, eliminating cross
contamination
Built in milling for precise
particle size specifications
Route Scouting, optimization, holistic
development, QBD, IP evaluation,
regulatory & CMC support.
Preclinical, early phase,
late phase
Screening, Optimization
& Stress Study
Payloads- Up to multi grams
Linkers-Up to multi kilograms
Payload-Linker-conjugate-Up to multi grams
